Intermedin inhibits unilateral ureteral obstruction-induced oxidative stress via NADPH oxidase Nox4 and cAMP-dependent mechanisms

NADPH oxidase Nox4-derived reactive oxygen species (ROS) play important roles in renal fibrosis. Our previous study demonstrated that intermedin (IMD) alleviated unilateral ureteral obstruction (UUO)-induced renal fibrosis by inhibition of ROS. However, the precise mechanisms remain unclear. Herein,...

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Detalles Bibliográficos
Autores principales: Qiao, Xi, Wang, Lihua, Wang, Yanhong, Su, Xiaole, Qi, Yue, Fan, Yun, Peng, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447914/
https://www.ncbi.nlm.nih.gov/pubmed/28805491
http://dx.doi.org/10.1080/0886022X.2017.1361839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447914/
https://www.ncbi.nlm.nih.gov/pubmed/28805491
http://dx.doi.org/10.1080/0886022X.2017.1361839

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