Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib

Background: Synovial fibroblasts (SF) play a major role in the pathogenesis of rheumatoid arthritis (RA) and develop an aggressive phenotype destroying cartilage and bone, thus termed RASF. JAK inhibitors have shown to be an efficient therapeutic option in RA treatment, but less is known about the e...

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Detalles Bibliográficos
Autores principales: Diller, Magnus, Hasseli, Rebecca, Hülser, Marie-Lisa, Aykara, Iris, Frommer, Klaus, Rehart, Stefan, Müller-Ladner, Ulf, Neumann, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448044/
https://www.ncbi.nlm.nih.gov/pubmed/30984167
http://dx.doi.org/10.3389/fimmu.2019.00541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448044/
https://www.ncbi.nlm.nih.gov/pubmed/30984167
http://dx.doi.org/10.3389/fimmu.2019.00541

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