Defective Induction of COX-2 Expression by Psoriatic Fibroblasts Promotes Pro-inflammatory Activation of Macrophages

Fibroblasts play an important role as members of the innate immune system through the secretion of COX-2-derived inflammatory mediators such as prostaglandin E(2) (PGE(2)). However, it has been described that dermal fibroblasts behave like mesenchymal stem cells reducing lymphocyte recruitment and d...

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Detalles Bibliográficos
Autores principales: Arasa, Jorge, Terencio, María Carmen, Andrés, Rosa María, Marín-Castejón, Asunción, Valcuende-Cavero, Francisca, Payá, Miguel, Montesinos, María Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448046/
https://www.ncbi.nlm.nih.gov/pubmed/30984165
http://dx.doi.org/10.3389/fimmu.2019.00536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448046/
https://www.ncbi.nlm.nih.gov/pubmed/30984165
http://dx.doi.org/10.3389/fimmu.2019.00536

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