Cargando…

Analysis of Mechanically Activated Ion Channels at the Cell-Substrate Interface: Combining Pillar Arrays and Whole-Cell Patch-Clamp

Ionic currents can be evoked by mechanical inputs applied directly at the cell-substrate interface. These ionic currents are mediated by mechanically activated ion channels, where the open probability increases with increasing mechanical input. In order to study mechanically activated ion channels d...

Descripción completa

Detalles Bibliográficos
Autores principales: Sianati, Setareh, Kurumlian, Anie, Bailey, Evan, Poole, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448047/
https://www.ncbi.nlm.nih.gov/pubmed/30984749
http://dx.doi.org/10.3389/fbioe.2019.00047