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Non-covalent proteasome inhibitor PI-1840 induces apoptosis and autophagy in osteosarcoma cells

Osteosarcoma (OS) is the predominant form of primary bone malignancy in children and adolescents. Although the combination of chemotherapy and modified surgical therapy leads to marked improvements in the survival rate, the therapeutic outcomes remain unsatisfactory. Therefore, the identification of...

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Detalles Bibliográficos
Autores principales: Chen, Yuxi, Chen, Hongjun, Xie, Hui, Yuan, Shaohui, Gao, Chuanbo, Yu, Lei, Bi, Zhenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448088/
https://www.ncbi.nlm.nih.gov/pubmed/30864717
http://dx.doi.org/10.3892/or.2019.7040