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Non-covalent proteasome inhibitor PI-1840 induces apoptosis and autophagy in osteosarcoma cells
Osteosarcoma (OS) is the predominant form of primary bone malignancy in children and adolescents. Although the combination of chemotherapy and modified surgical therapy leads to marked improvements in the survival rate, the therapeutic outcomes remain unsatisfactory. Therefore, the identification of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448088/ https://www.ncbi.nlm.nih.gov/pubmed/30864717 http://dx.doi.org/10.3892/or.2019.7040 |