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Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation

Uterine serous carcinoma (USC) is a subtype of endometrial cancer. Compared with endometrial endometroid carcinoma, the majority of USC cases are more aggressive. Cyclin-dependent kinase inhibitor 2A (P16INK4A) is a canonical tumor suppressor that blocks cell cycle progression; however, P16INK4A is...

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Detalles Bibliográficos
Autores principales: Xiao, Zhen, He, Yingying, Liu, Chongya, Xiang, Lin, Yi, Jingyan, Wang, Min, Shen, Tingting, Shen, Lanlin, Xue, Yijue, Shi, Hong, Liu, Pixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448098/
https://www.ncbi.nlm.nih.gov/pubmed/30896884
http://dx.doi.org/10.3892/or.2019.7067