Selective Cytotoxicity to HER2 Positive Breast Cancer Cells by Saporin-Loaded Nanobody-Targeted Polymeric Nanoparticles in Combination with Photochemical Internalization

[Image: see text] In cancer treatment, polymeric nanoparticles (NPs) can serve as a vehicle for the delivery of cytotoxic proteins that have intracellular targets but that lack well-defined mechanisms for cellular internalization, such as saporin. In this work, we have prepared PEGylated poly(lactic...

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Detalles Bibliográficos
Autores principales: Martínez-Jothar, Lucía, Beztsinna, Nataliia, van Nostrum, Cornelus F., Hennink, Wim E., Oliveira, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448105/
https://www.ncbi.nlm.nih.gov/pubmed/30817164
http://dx.doi.org/10.1021/acs.molpharmaceut.8b01318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448105/
https://www.ncbi.nlm.nih.gov/pubmed/30817164
http://dx.doi.org/10.1021/acs.molpharmaceut.8b01318

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