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Core Outcome Measures in Preclinical Assessment of Candidate Analgesics
All preclinical procedures for analgesic drug discovery involve two components: 1) a “pain stimulus” (the principal independent variable), which is delivered to an experimental subject with the intention of producing a pain state; and 2) a “pain behavior” (the principal dependent variable), which is...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Pharmacology and Experimental Therapeutics
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448246/ https://www.ncbi.nlm.nih.gov/pubmed/30898855 http://dx.doi.org/10.1124/pr.118.017210 |