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Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors
BACKGROUND: Although vaccines for hepatitis B virus (HBV) are highly effective, HBV infections in vaccinees occur. Index samples of breakthrough infections are typically anti-HBc negative but HBV DNA positive with protective anti-HBs levels while HBsAg detection may be delayed or absent. HBsAg mutat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448254/ https://www.ncbi.nlm.nih.gov/pubmed/30943997 http://dx.doi.org/10.1186/s12985-019-1154-4 |