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Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors

BACKGROUND: Although vaccines for hepatitis B virus (HBV) are highly effective, HBV infections in vaccinees occur. Index samples of breakthrough infections are typically anti-HBc negative but HBV DNA positive with protective anti-HBs levels while HBsAg detection may be delayed or absent. HBsAg mutat...

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Detalles Bibliográficos
Autores principales: Kuhns, Mary C., McNamara, Anne L., Holzmayer, Vera, Cloherty, Gavin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448254/
https://www.ncbi.nlm.nih.gov/pubmed/30943997
http://dx.doi.org/10.1186/s12985-019-1154-4