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Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas
Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are necessary for accurate risk stratification in the non-WNT subgroups due to the underlying heterogeneity in genetic alterations and overall s...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448261/ https://www.ncbi.nlm.nih.gov/pubmed/30944042 http://dx.doi.org/10.1186/s40478-019-0697-3 |