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Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas

Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are necessary for accurate risk stratification in the non-WNT subgroups due to the underlying heterogeneity in genetic alterations and overall s...

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Detalles Bibliográficos
Autores principales: Bharambe, Harish Shrikrishna, Paul, Raikamal, Panwalkar, Pooja, Jalali, Rakesh, Sridhar, Epari, Gupta, Tejpal, Moiyadi, Aliasgar, Shetty, Prakash, Kazi, Sadaf, Deogharkar, Akash, Masurkar, Shalaka, Yogi, Kedar, Kunder, Ratika, Gadewal, Nikhil, Goel, Atul, Goel, Naina, Chinnaswamy, Girish, Ramaswamy, Vijay, Shirsat, Neelam Vishwanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448261/
https://www.ncbi.nlm.nih.gov/pubmed/30944042
http://dx.doi.org/10.1186/s40478-019-0697-3