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Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability

BACKGROUND: The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain, possibly providing greater cell specificity and low toxic...

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Detalles Bibliográficos
Autores principales: Spinelli, Antonello, Girelli, Maria, Arosio, Daniela, Polito, Laura, Podini, Paola, Martino, Gianvito, Seneci, Pierfausto, Muzio, Luca, Menegon, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448280/
https://www.ncbi.nlm.nih.gov/pubmed/30943991
http://dx.doi.org/10.1186/s12951-019-0481-3