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Intracisternal delivery of PEG-coated gold nanoparticles results in high brain penetrance and long-lasting stability
BACKGROUND: The increasing use of gold nanoparticles (AuNPs) in the field of neuroscience instilled hope for their rapid translation to the clinical practice. AuNPs can be engineered to carry therapeutics or diagnostics in the diseased brain, possibly providing greater cell specificity and low toxic...
Autores principales: | Spinelli, Antonello, Girelli, Maria, Arosio, Daniela, Polito, Laura, Podini, Paola, Martino, Gianvito, Seneci, Pierfausto, Muzio, Luca, Menegon, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448280/ https://www.ncbi.nlm.nih.gov/pubmed/30943991 http://dx.doi.org/10.1186/s12951-019-0481-3 |
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