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A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction
STUDY OBJECTIVES: Chronic sleep restriction in adolescents is widespread, yet we know little about how to apportion the limited amount of sleep obtained to minimize cognitive impairment: should sleep occur only nocturnally, or be split across separate nocturnal and daytime nap periods? This is parti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448285/ https://www.ncbi.nlm.nih.gov/pubmed/30715485 http://dx.doi.org/10.1093/sleep/zsz018 |
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author | Cousins, James N Van Rijn, Elaine Ong, Ju Lynn Chee, Michael W L |
author_facet | Cousins, James N Van Rijn, Elaine Ong, Ju Lynn Chee, Michael W L |
author_sort | Cousins, James N |
collection | PubMed |
description | STUDY OBJECTIVES: Chronic sleep restriction in adolescents is widespread, yet we know little about how to apportion the limited amount of sleep obtained to minimize cognitive impairment: should sleep occur only nocturnally, or be split across separate nocturnal and daytime nap periods? This is particularly relevant to hippocampal-dependent cognitive functions that underpin several aspects of learning. METHOD: We assessed hippocampal function in four groups by evaluating short-term topographical memory with the Four Mountains Test (4MT). All participants began with 9 hours nocturnal time-in-bed (TIB) for 2 days before following different sleep schedules over the next 3 days. Each day, one group had 5 hours nocturnal TIB (5.0h; n = 30), another, 6.5 hours nocturnal TIB (6.5h; n = 29), and a third had 6.5 hours split into 5 hours nocturnal TIB and a 1.5 hour TIB daytime nap (5.0 + 1.5h; n = 29). A control group maintained 9 hours nocturnal TIB (9.0h; n = 30). The 4MT was administered mid-afternoon (1.5 hours after awakening for those who napped). RESULTS: Performance of the 5.0h and 6.5h nocturnal TIB groups was significantly impaired relative to the 9.0h control group. Performance of participants on the split- sleep schedule (5.0 + 1.5h) did not significantly differ from controls. CONCLUSIONS: These findings suggest that hippocampal function is sensitive to moderate multi-night sleep restriction, but deficits can be ameliorated by splitting sleep, at least for a period after waking from a daytime nap. While this split sleep schedule should not be considered a replacement for adequate nocturnal sleep, it appears to benefit the cognitive and neurophysiological functions that underpin learning in those who are chronically sleep deprived. |
format | Online Article Text |
id | pubmed-6448285 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-64482852019-04-08 A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction Cousins, James N Van Rijn, Elaine Ong, Ju Lynn Chee, Michael W L Sleep Cognitive, Affective and Behavioral Neuroscience of Sleep STUDY OBJECTIVES: Chronic sleep restriction in adolescents is widespread, yet we know little about how to apportion the limited amount of sleep obtained to minimize cognitive impairment: should sleep occur only nocturnally, or be split across separate nocturnal and daytime nap periods? This is particularly relevant to hippocampal-dependent cognitive functions that underpin several aspects of learning. METHOD: We assessed hippocampal function in four groups by evaluating short-term topographical memory with the Four Mountains Test (4MT). All participants began with 9 hours nocturnal time-in-bed (TIB) for 2 days before following different sleep schedules over the next 3 days. Each day, one group had 5 hours nocturnal TIB (5.0h; n = 30), another, 6.5 hours nocturnal TIB (6.5h; n = 29), and a third had 6.5 hours split into 5 hours nocturnal TIB and a 1.5 hour TIB daytime nap (5.0 + 1.5h; n = 29). A control group maintained 9 hours nocturnal TIB (9.0h; n = 30). The 4MT was administered mid-afternoon (1.5 hours after awakening for those who napped). RESULTS: Performance of the 5.0h and 6.5h nocturnal TIB groups was significantly impaired relative to the 9.0h control group. Performance of participants on the split- sleep schedule (5.0 + 1.5h) did not significantly differ from controls. CONCLUSIONS: These findings suggest that hippocampal function is sensitive to moderate multi-night sleep restriction, but deficits can be ameliorated by splitting sleep, at least for a period after waking from a daytime nap. While this split sleep schedule should not be considered a replacement for adequate nocturnal sleep, it appears to benefit the cognitive and neurophysiological functions that underpin learning in those who are chronically sleep deprived. Oxford University Press 2019-02-04 /pmc/articles/PMC6448285/ /pubmed/30715485 http://dx.doi.org/10.1093/sleep/zsz018 Text en © Sleep Research Society 2019. Published by Oxford University Press [on behalf of the Sleep Research Society]. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Cognitive, Affective and Behavioral Neuroscience of Sleep Cousins, James N Van Rijn, Elaine Ong, Ju Lynn Chee, Michael W L A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title | A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title_full | A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title_fullStr | A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title_full_unstemmed | A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title_short | A split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
title_sort | split sleep schedule rescues short-term topographical memory after multiple nights of sleep restriction |
topic | Cognitive, Affective and Behavioral Neuroscience of Sleep |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448285/ https://www.ncbi.nlm.nih.gov/pubmed/30715485 http://dx.doi.org/10.1093/sleep/zsz018 |
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