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Evidence of Local Concentration of α-Particles from (211)At-Labeled Antibodies in Liver Metastasis Tissue

We investigated the local concentration of α-particles from (211)At-labeled trastuzumab antibodies against human epidermal growth factor receptor type 2 antigens in liver metastasis tissue of mice. Methods: Mice carrying metastatic cancer in their liver were injected with (211)At-agent. After 12 h,...

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Detalles Bibliográficos
Autores principales: Kodaira, Satoshi, Morokoshi, Yukie, Li, Huizi Keiko, Konishi, Teruaki, Kurano, Mieko, Hasegawa, Sumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448461/
https://www.ncbi.nlm.nih.gov/pubmed/30291193
http://dx.doi.org/10.2967/jnumed.118.216853