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Formulation design, characterization, and in vitro and in vivo evaluation of nanostructured lipid carriers containing a bile salt for oral delivery of gypenosides

BACKGROUND: Gypenosides (GPS) have been used as traditional medicine for centuries with various pharmacological effects. However, its therapeutic effects were restricted owing to the poor lipid and water solubility and low absorption. This study aimed to develop nanostructured lipid carriers (NLCs)...

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Detalles Bibliográficos
Autores principales: Yang, Gang, Wu, Feihua, Chen, Minyan, Jin, Jian, Wang, Rong, Yuan, Yongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448534/
https://www.ncbi.nlm.nih.gov/pubmed/31015758
http://dx.doi.org/10.2147/IJN.S194934