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Formaldehyde Induces Mesenteric Artery Relaxation via a Sensitive Transient Receptor Potential Ankyrin-1 (TRPA1) and Endothelium-Dependent Mechanism: Potential Role in Postprandial Hyperemia

Formaldehyde (FA), the smallest aldehyde, is generated endogenously, and is widespread in the environment in foods, beverages and as a gas phase product of incomplete combustion. The main metabolite of FA, formate, was increased significantly in murine urine (∼3×) after overnight feeding. Because fe...

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Detalles Bibliográficos
Autores principales: Jin, L., Jagatheesan, G., Guo, L., Nystoriak, M., Malovichko, M., Lorkiewicz, P., Bhatnagar, A., Srivastava, S., Conklin, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448550/
https://www.ncbi.nlm.nih.gov/pubmed/30984013
http://dx.doi.org/10.3389/fphys.2019.00277