Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

Emerging notion in carcinogenesis ascribes tumor initiation and aggressiveness to cancer stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be compatible with CSCs hypothesis. Mutations in p53 are highly frequent in CRC, and are known to facilitate tumor development an...

Descripción completa

Detalles Bibliográficos
Autores principales: Solomon, Hilla, Dinowitz, Nathan, Pateras, loannis S., Cooks, Tomer, Shetzer, Yoav, Molchadsky, Alina, Charni, Meital, Rabani, Stav, Koifman, Gabriela, Tarcic, Ohad, Porat, Ziv, Kogan-Sakin, Ira, Goldfinger, Naomi, Oren, Moshe, Harris, Curtis C., Gorgoulis, Vassilis G., Rotter, Varda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448595/
https://www.ncbi.nlm.nih.gov/pubmed/29343849
http://dx.doi.org/10.1038/s41388-017-0060-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448595/
https://www.ncbi.nlm.nih.gov/pubmed/29343849
http://dx.doi.org/10.1038/s41388-017-0060-8

Ejemplares similares