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Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth

Administration of sclerostin-neutralizing antibody (Scl-Ab) treatment has been shown to elicit an anabolic bone response in growing and adult mice. Prior work characterized the response of individual mouse strains but did not establish whether the impact of Scl-Ab on whole bone strength would vary a...

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Detalles Bibliográficos
Autores principales: Mathis, Noah J., Adaniya, Emily N., Smith, Lauren M., Robling, Alexander G., Jepsen, Karl J., Schlecht, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448823/
https://www.ncbi.nlm.nih.gov/pubmed/30947279
http://dx.doi.org/10.1371/journal.pone.0214520