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Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays

Preventive viral vaccine efficacy trials require large-scale sample analysis to quantitate immune responses and their correlation with infection outcomes. Traditional plaque reduction assays measure a functionally important form of humoral immunity, neutralizing antibody titer. These assays, however...

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Detalles Bibliográficos
Autores principales: Blevins, Tamara P., Yu, Yinyi, Belshe, Robert B., Bellamy, Abbie R., Morrison, Lynda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448825/
https://www.ncbi.nlm.nih.gov/pubmed/30946751
http://dx.doi.org/10.1371/journal.pone.0214467