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DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS)
Whole-genome bisulfite sequencing (WGBS) and reduced representation bisulfite sequencing (RRBS) are widely used for measuring DNA methylation levels on a genome-wide scale. Both methods have limitations: WGBS is expensive and prohibitive for most large-scale projects; RRBS only interrogates 6–12% of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448829/ https://www.ncbi.nlm.nih.gov/pubmed/30946758 http://dx.doi.org/10.1371/journal.pone.0214368 |