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GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors

α7 Nicotinic acetylcholine receptors (nAChRs) reportedly reduce inflammation by blocking effects of the important pro-inflammatory transcription factor, nuclear factor kappa-light chain-enhancer of B cells (NFκB). The α7 nAChR partial agonist GTS-21 reduces secretion of pro-inflammatory cytokines in...

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Detalles Bibliográficos
Autores principales:	Garg, Brijesh K., Loring, Ralph H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448884/ https://www.ncbi.nlm.nih.gov/pubmed/30947238 http://dx.doi.org/10.1371/journal.pone.0214942

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