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Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

Type 1 diabetes is an autoimmune disease characterised by the destruction of insulin producing beta cells in the pancreas. Whilst it remains unclear what the original triggering factors for this destruction are, observations from the natural history of human type 1 diabetes, including incidence rate...

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Detalles Bibliográficos
Autores principales: Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448885/
https://www.ncbi.nlm.nih.gov/pubmed/28770318
http://dx.doi.org/10.1007/s00125-017-4377-1