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The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

AIMS/HYPOTHESIS: The aim of this study was to determine whether therapy with the cytokine IL-22 could be used to prevent the development of, or treat, autoimmune diabetes in the NOD mouse. METHODS: Six-week-old NOD mice were administered bi-weekly either recombinant mouse IL-22 (200 ng/g) or PBS (ve...

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Detalles Bibliográficos
Autores principales: Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A., Hasnain, Sumaira Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448904/
https://www.ncbi.nlm.nih.gov/pubmed/28779211
http://dx.doi.org/10.1007/s00125-017-4392-2