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Evidence-based prioritisation and enrichment of genes interacting with metformin in type 2 diabetes

AIMS/HYPOTHESIS: There is an extensive body of literature suggesting the involvement of multiple loci in regulating the action of metformin; most findings lack replication, without which distinguishing true-positive from false-positive findings is difficult. To address this, we undertook evidence-ba...

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Detalles Bibliográficos
Autores principales: Dawed, Adem Y., Ali, Ashfaq, Zhou, Kaixin, Pearson, Ewan R., Franks, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448905/
https://www.ncbi.nlm.nih.gov/pubmed/28842730
http://dx.doi.org/10.1007/s00125-017-4404-2