HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response

Differentiation of secretory cells leads to sharp increases in protein synthesis, challenging endoplasmic reticulum (ER) proteostasis. Anticipatory activation of the unfolded protein response (UPR) prepares cells for the onset of secretory function by expanding the ER size and folding capacity. How...

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Detalles Bibliográficos
Autores principales: Zha, Ji, Ying, Mingjie, Alexander-Floyd, Jasmine, Gidalevitz, Tali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448932/
https://www.ncbi.nlm.nih.gov/pubmed/30908491
http://dx.doi.org/10.1371/journal.pbio.3000196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448932/
https://www.ncbi.nlm.nih.gov/pubmed/30908491
http://dx.doi.org/10.1371/journal.pbio.3000196

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