Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

AIMS/HYPOTHESIS: Angiopoietin-like 4 (ANGPTL4) is an important regulator of triacylglycerol metabolism, carrying out this role by inhibiting the enzymes lipoprotein lipase and pancreatic lipase. ANGPTL4 is a potential target for ameliorating cardiometabolic diseases. Although ANGPTL4 has been implic...

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Detalles Bibliográficos
Autores principales: Janssen, Aafke W. F., Katiraei, Saeed, Bartosinska, Barbara, Eberhard, Daniel, Willems van Dijk, Ko, Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449003/
https://www.ncbi.nlm.nih.gov/pubmed/29502266
http://dx.doi.org/10.1007/s00125-018-4583-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449003/
https://www.ncbi.nlm.nih.gov/pubmed/29502266
http://dx.doi.org/10.1007/s00125-018-4583-5

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