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Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

AIMS/HYPOTHESIS: Angiopoietin-like 4 (ANGPTL4) is an important regulator of triacylglycerol metabolism, carrying out this role by inhibiting the enzymes lipoprotein lipase and pancreatic lipase. ANGPTL4 is a potential target for ameliorating cardiometabolic diseases. Although ANGPTL4 has been implic...

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Detalles Bibliográficos
Autores principales:	Janssen, Aafke W. F., Katiraei, Saeed, Bartosinska, Barbara, Eberhard, Daniel, Willems van Dijk, Ko, Kersten, Sander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449003/ https://www.ncbi.nlm.nih.gov/pubmed/29502266 http://dx.doi.org/10.1007/s00125-018-4583-5

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