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PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation

Regenerated cartilage formed after Autologous Chondrocyte Implantation may be of suboptimal quality due to postulated hypertrophic changes. Parathyroid hormone-related peptide, containing the parathyroid hormone sequence (PTHrP 1–34), enhances cartilage growth during development and inhibits hypertr...

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Detalles Bibliográficos
Autores principales: Rutgers, Marijn, Bach, Frances, Vonk, Luciënne, van Rijen, Mattie, Akrum, Vanessa, van Boxtel, Antonette, Dhert, Wouter, Creemers, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449021/
https://www.ncbi.nlm.nih.gov/pubmed/30947269
http://dx.doi.org/10.1371/journal.pone.0213483