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PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation
Regenerated cartilage formed after Autologous Chondrocyte Implantation may be of suboptimal quality due to postulated hypertrophic changes. Parathyroid hormone-related peptide, containing the parathyroid hormone sequence (PTHrP 1–34), enhances cartilage growth during development and inhibits hypertr...
Autores principales: | Rutgers, Marijn, Bach, Frances, Vonk, Luciënne, van Rijen, Mattie, Akrum, Vanessa, van Boxtel, Antonette, Dhert, Wouter, Creemers, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449021/ https://www.ncbi.nlm.nih.gov/pubmed/30947269 http://dx.doi.org/10.1371/journal.pone.0213483 |
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