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Dissociation rate compensation mechanism for budding yeast pioneer transcription factors

Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement. To understand this process mechanistically, we investigated tw...

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Detalles Bibliográficos
Autores principales: Donovan, Benjamin T, Chen, Hengye, Jipa, Caroline, Bai, Lu, Poirier, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449090/
https://www.ncbi.nlm.nih.gov/pubmed/30888317
http://dx.doi.org/10.7554/eLife.43008