Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network

Hypothalamic POMC deficiency leads to obesity and metabolic deficiencies, largely due to the loss of melanocortin peptides. However, POMC neurons in the arcuate nucleus (ARC) are comprised of glutamatergic and GABAergic subpopulations. The developmental program, relative proportion and function of t...

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Detalles Bibliográficos
Autores principales: Jones, Graham L., Wittmann, Gábor, Yokosawa, Eva B., Yu, Hui, Mercer, Aaron J., Lechan, Ronald M., Low, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449166/
https://www.ncbi.nlm.nih.gov/pubmed/30957016
http://dx.doi.org/10.1523/ENEURO.0400-18.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449166/
https://www.ncbi.nlm.nih.gov/pubmed/30957016
http://dx.doi.org/10.1523/ENEURO.0400-18.2019

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