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Single-molecule characterization of extrinsic transcription termination by Sen1 helicase

Extrinsic transcription termination typically involves remodeling of RNA polymerase by an accessory helicase. In yeast this is accomplished by the Sen1 helicase homologous to human senataxin (SETX). To gain insight into these processes we develop a DNA scaffold construct compatible with magnetic-tra...

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Detalles Bibliográficos
Autores principales: Wang, S., Han, Z., Libri, D., Porrua, O., Strick, T. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449345/
https://www.ncbi.nlm.nih.gov/pubmed/30948716
http://dx.doi.org/10.1038/s41467-019-09560-9