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Single-molecule characterization of extrinsic transcription termination by Sen1 helicase
Extrinsic transcription termination typically involves remodeling of RNA polymerase by an accessory helicase. In yeast this is accomplished by the Sen1 helicase homologous to human senataxin (SETX). To gain insight into these processes we develop a DNA scaffold construct compatible with magnetic-tra...
Autores principales: | Wang, S., Han, Z., Libri, D., Porrua, O., Strick, T. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449345/ https://www.ncbi.nlm.nih.gov/pubmed/30948716 http://dx.doi.org/10.1038/s41467-019-09560-9 |
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