Lower synaptic density is associated with depression severity and network alterations

Synaptic loss and deficits in functional connectivity are hypothesized to contribute to symptoms associated with major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). The synaptic vesicle glycoprotein 2A (SV2A) can be used to index the number of nerve terminals, an indirect esti...

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Detalles Bibliográficos
Autores principales: Holmes, Sophie E., Scheinost, Dustin, Finnema, Sjoerd J., Naganawa, Mika, Davis, Margaret T., DellaGioia, Nicole, Nabulsi, Nabeel, Matuskey, David, Angarita, Gustavo A., Pietrzak, Robert H., Duman, Ronald S., Sanacora, Gerard, Krystal, John H., Carson, Richard E., Esterlis, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449365/
https://www.ncbi.nlm.nih.gov/pubmed/30948709
http://dx.doi.org/10.1038/s41467-019-09562-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449365/
https://www.ncbi.nlm.nih.gov/pubmed/30948709
http://dx.doi.org/10.1038/s41467-019-09562-7

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