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Three-dimensional imaging and quantitative analysis in CLARITY processed breast cancer tissues

The tumor microenvironment can be spatially heterogenous, which makes it challenging to fully characterize with standard 2D histology-based methods. In this study, we determined the feasibility of a CLARITY tissue-processing approach to analyze biopsies from breast cancer patients. Formalin-fixed hu...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Shen, Qi, White, Sharla L., Gokmen-Polar, Yesim, Badve, Sunil, Goodman, Laurie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449377/
https://www.ncbi.nlm.nih.gov/pubmed/30948791
http://dx.doi.org/10.1038/s41598-019-41957-w