Identification of the kinase STK25 as an upstream activator of LATS signaling

The Hippo pathway maintains tissue homeostasis by negatively regulating the oncogenic transcriptional co-activators YAP and TAZ. Though functional inactivation of the Hippo pathway is common in tumors, mutations in core pathway components are rare. Thus, understanding how tumor cells inactivate Hipp...

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Detalles Bibliográficos
Autores principales: Lim, Sanghee, Hermance, Nicole, Mudianto, Tenny, Mustaly, Hatim M., Mauricio, Ian Paolo Morelos, Vittoria, Marc A., Quinton, Ryan J., Howell, Brian W., Cornils, Hauke, Manning, Amity L., Ganem, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449379/
https://www.ncbi.nlm.nih.gov/pubmed/30948712
http://dx.doi.org/10.1038/s41467-019-09597-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449379/
https://www.ncbi.nlm.nih.gov/pubmed/30948712
http://dx.doi.org/10.1038/s41467-019-09597-w

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