Identification of the kinase STK25 as an upstream activator of LATS signaling

The Hippo pathway maintains tissue homeostasis by negatively regulating the oncogenic transcriptional co-activators YAP and TAZ. Though functional inactivation of the Hippo pathway is common in tumors, mutations in core pathway components are rare. Thus, understanding how tumor cells inactivate Hipp...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Sanghee, Hermance, Nicole, Mudianto, Tenny, Mustaly, Hatim M., Mauricio, Ian Paolo Morelos, Vittoria, Marc A., Quinton, Ryan J., Howell, Brian W., Cornils, Hauke, Manning, Amity L., Ganem, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449379/
https://www.ncbi.nlm.nih.gov/pubmed/30948712
http://dx.doi.org/10.1038/s41467-019-09597-w

Ejemplares similares

Ejemplares similares