Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation

The response of childhood acute lymphoblastic leukemia (ALL) to dexamethasone predicts the long-term remission outcome. To explore the mechanisms of dexamethasone resistance in B cell ALL (B-ALL), we generated dexamethasone-resistant clones by prolonged treatment with dexamethasone. Using RNA-sequen...

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Detalles Bibliográficos
Autores principales: Chougule, Rohit A., Shah, Kinjal, Moharram, Sausan A., Vallon-Christersson, Johan, Kazi, Julhash U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449402/
https://www.ncbi.nlm.nih.gov/pubmed/30962949
http://dx.doi.org/10.1038/s41525-019-0082-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449402/
https://www.ncbi.nlm.nih.gov/pubmed/30962949
http://dx.doi.org/10.1038/s41525-019-0082-y

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