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Epigenetic Enzyme Mutations: Role in Tumorigenesis and Molecular Inhibitors

Epigenetic modifications, such as DNA methylation and histone modification, result in heritable changes in gene expression without changing the DNA sequence. Epigenetic regulatory enzymes such as DNA methyltransferases, histone methyltransferases, and histone deacetylases are involved in epigenetic...

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Detalles Bibliográficos
Autores principales: Han, Mei, Jia, Lina, Lv, Wencai, Wang, Lihui, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449417/
https://www.ncbi.nlm.nih.gov/pubmed/30984620
http://dx.doi.org/10.3389/fonc.2019.00194