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Epigenetic Enzyme Mutations: Role in Tumorigenesis and Molecular Inhibitors
Epigenetic modifications, such as DNA methylation and histone modification, result in heritable changes in gene expression without changing the DNA sequence. Epigenetic regulatory enzymes such as DNA methyltransferases, histone methyltransferases, and histone deacetylases are involved in epigenetic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449417/ https://www.ncbi.nlm.nih.gov/pubmed/30984620 http://dx.doi.org/10.3389/fonc.2019.00194 |