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The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

Follicular helper T cells (TFH cells), known as the primary “helpers” of the germinal center (GC) reaction, promote the humoral immune response to defend against various pathogens. Under conditions of infection by different types of pathogens, many shared transcription factors (TFs), such as Bcl-6,...

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Detalles Bibliográficos
Autores principales: Wang, Pengcheng, Wang, Youping, Xie, Luoyingzi, Xiao, Minglu, Wu, Jialin, Xu, Lifan, Bai, Qiang, Hao, Yaxing, Huang, Qizhao, Chen, Xiangyu, He, Ran, Li, Baohua, Yang, Sen, Chen, Yaokai, Wu, Yuzhang, Ye, Lilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449430/
https://www.ncbi.nlm.nih.gov/pubmed/30984183
http://dx.doi.org/10.3389/fimmu.2019.00606