Attenuation of Novelty-Induced Hyperactivity of Gria1-/- Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics

Gene-targeted mice with deficient AMPA receptor GluA1 subunits (Gria1-/- mice) show robust hyperlocomotion in a novel environment, suggesting them to constitute a model for hyperactivity disorders such as mania, schizophrenia and attention deficit hyperactivity disorder. This behavioral alteration h...

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Detalles Bibliográficos
Autores principales: Aitta-aho, Teemu, Maksimovic, Milica, Dahl, Kristiina, Sprengel, Rolf, Korpi, Esa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449460/
https://www.ncbi.nlm.nih.gov/pubmed/30984001
http://dx.doi.org/10.3389/fphar.2019.00309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449460/
https://www.ncbi.nlm.nih.gov/pubmed/30984001
http://dx.doi.org/10.3389/fphar.2019.00309

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