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Time of Day and a Ketogenic Diet Influence Susceptibility to SUDEP in Scn1a(R1407X/+) Mice

Sudden unexpected death in epilepsy (SUDEP) is a major cause of mortality in patients with drug-resistant epilepsy. Most SUDEP cases occur in bed at night and are preceded by a generalized tonic-clonic seizure (GTCS). Dravet syndrome (DS) is a severe childhood-onset epilepsy commonly caused by mutat...

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Detalles Bibliográficos
Autores principales: Teran, Frida A., Kim, YuJaung, Crotts, Megan S., Bravo, Eduardo, Emaus, Katlynn J., Richerson, George B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449461/
https://www.ncbi.nlm.nih.gov/pubmed/30984098
http://dx.doi.org/10.3389/fneur.2019.00278