Deciphering the role of trehalose in hindering antithrombin polymerization

Serine protease inhibitors (serpins) family have a complex mechanism of inhibition that requires a large scale conformational change. Antithrombin (AT), a member of serpin superfamily serves as a key regulator of the blood coagulation cascade, deficiency of which leads to thrombosis. In recent years...

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Detalles Bibliográficos
Autores principales: Naseem, Asma, Khan, Mohammad Sazzad, Ali, Hashim, Ahmad, Irshad, Jairajpuri, Mohamad Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449516/
https://www.ncbi.nlm.nih.gov/pubmed/30886063
http://dx.doi.org/10.1042/BSR20182259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449516/
https://www.ncbi.nlm.nih.gov/pubmed/30886063
http://dx.doi.org/10.1042/BSR20182259

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