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Knockdown of lncRNA HOTAIR sensitizes breast cancer cells to ionizing radiation through activating miR-218

Radiotherapy is a major therapeutic strategy for breast cancer, while cancer radioresistance remains an obstacle for the successful control of the tumor. Novel radiosensitizing targets are to be developed to overcome radioresistance. Recently, long non-coding RNAs (lncRNAs) were proved to play criti...

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Detalles Bibliográficos
Autores principales: Hu, Xuguang, Ding, Dan, Zhang, Jiayi, Cui, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449517/
https://www.ncbi.nlm.nih.gov/pubmed/30429228
http://dx.doi.org/10.1042/BSR20181038