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Ubiquitination as a Key Regulator of Endosomal Signaling by GPCRs

G protein-coupled receptors (GPCRs) represent the largest family of therapeutic targets for FDA approved drugs. Therefore, understanding the molecular regulation of their signaling pathways is of paramount importance. Similarly, the mitogen activated protein kinase (MAPK) p38 is a critical mediator...

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Detalles Bibliográficos
Autores principales: Burton, Jeremy C., Grimsey, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449645/
https://www.ncbi.nlm.nih.gov/pubmed/30984758
http://dx.doi.org/10.3389/fcell.2019.00043