Improving protein function prediction using protein sequence and GO-term similarities

MOTIVATION: Most automatic functional annotation methods assign Gene Ontology (GO) terms to proteins based on annotations of highly similar proteins. We advocate that proteins that are less similar are still informative. Also, despite their simplicity and structure, GO terms seem to be hard for comp...

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Detalles Bibliográficos
Autores principales: Makrodimitris, Stavros, van Ham, Roeland C H J, Reinders, Marcel J T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449755/
https://www.ncbi.nlm.nih.gov/pubmed/30169569
http://dx.doi.org/10.1093/bioinformatics/bty751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449755/
https://www.ncbi.nlm.nih.gov/pubmed/30169569
http://dx.doi.org/10.1093/bioinformatics/bty751

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