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Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development

Nicotine, the main chemical constituent of tobacco, is highly detrimental to the developing fetus by increasing the risk of gestational complications and organ disorders. The effects of nicotine on human embryonic development and related mechanisms, however, remain poorly understood. Here, we perfor...

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Detalles Bibliográficos
Autores principales: Guo, Hongchao, Tian, Lei, Zhang, Joe Z., Kitani, Tomoya, Paik, David T., Lee, Won Hee, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449785/
https://www.ncbi.nlm.nih.gov/pubmed/30827876
http://dx.doi.org/10.1016/j.stemcr.2019.01.022