Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

BACKGROUND: Transgenic mice have been used extensively to analyze gene function. Unfortunately, traditional transgenic procedures have only limited use in analyzing alleles that cause lethality because lines of founder mice cannot be established. This is frustrating given that such alleles often rev...

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Detalles Bibliográficos
Autores principales: Misra, Ravi P, Bronson, Sarah K, Xiao, Qi, Garrison, Wendy, Li, Jixuan, Zhao, Roong, Duncan, Stephen A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64498/
https://www.ncbi.nlm.nih.gov/pubmed/11782291
http://dx.doi.org/10.1186/1472-6750-1-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64498/
https://www.ncbi.nlm.nih.gov/pubmed/11782291
http://dx.doi.org/10.1186/1472-6750-1-12

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